If necessary, 100 mg may be administered for the first dose only. After a satisfactory response has been obtained, dosage should be reduced to the minimum dose that provides continuing control of symptoms, usually 75 to 100 mg a day in three divided doses. After a satisfactory response has been what is voltaren retard, dosage should be reduced to the minimum dose that provides continuing control of symptoms. Rheumatoid arthritis225 mg per day. Osteoarthritis150 mg per day; higher doses have not been studied.