This medication it is not applicable with condition such as hyper sensitivity, allergic tendency, inflammation in the intestine, stomach or gastronomical bleeding, insufficiency in liver, renal insufficiency. In those patients who are having hepatic porphyria should be careful taking the medication or could result to side effects. When this medication is taken you must inform your doctor of you have an allergic reaction to the drug.

But it is not advisable that the drug will be applied to areas where cuts and wounds are present, for it may cause burning sensation and uncomfortable situation. Before applying the gel the area should be clean so that it could not result to infections. Some the effects are hepatic problem, gastrointestinal problem, renal problems and various other problems which includes cardiac problems.

Never put this medication in a refrigerator or in a very high temperature that may affect the drug. This must be discharge in a proper disposal area after using the drug. Have this storage every after you have this medication so that it could not damage the drug.

This medication is very effective when a patient is suffering from acute pain, just apply it and the pain could be relieve in a instant. This medication could give cooling sensation and ease as you apply it on the patient. This can also be used in condition migraine pains, with operative and post traumatic pain.

This is drug is in fact useful in situation where there is an inflammation and menstrual pain for women. But the application of this drug is applying it in area that is affected when you have this feeling or pain or a sensation of pain. This can be generally applied twice a day except when it is needed or the pain should be treated immediately.